Transform Deadly Cancer into a Chronic and Eventually Curable Disease
Transform Deadly Cancer into a Chronic and Eventually Curable Disease
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About Us
About Us
Company Overview
Adlai Nortye (NASDAQ: ANL) is a global clinical-stage company focused on the development of innovative targeted and immune- modulating cancer therapies, with global R&D centers in the U.S. and China. The Company is advancing a robust oncology pipeline, with our lead candidate Buparlisib (AN2025), a pan-PI3K inhibitor, currently being evaluated in a registrational Phase 3 trial (NCT04338399) in patients with recurrent or static head and neck squamous cell cancer (HNSCC) that has progressed after prior anti-PD(L)1 treatment. Additionally, we are advancing multiple drug candidates including AN4005, an oral small molecule PD-L1 inhibitor, AN8025, a trifunctional fusion protein (αPD-L1/Lag3v/CD86v) acting as a T cell and antigen-presenting cell modulator, and AN9025, an oral small molecule pan-RAS(ON) inhibitor.
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Differentiated Pipeline
We have identified and developed a robust pipeline. Currently, our pipeline includes two clinical-stage drug candidates, buparlisib (AN2025) and AN4005 (oral anti-PD-L1); as well as two IND-enabling stage candidates, AN8025 (tri-specific immune-oncology modulator) and AN9025 (pan-RAS(ON) inhibitor).
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