PIPELINE
The clinical-stage assets are shown as below. There are also ten plus pre-clinical assets in our pipeline. 
  • Product Indication Progress
  • Discovery Pre-clinical Phase1 Phase2 Phase3  
  • AN1004 (Pelareorep) breast cancer  

    Pelareorep is a safe and well-tolerated intravenously delivered immuno-oncolytic virus (IOV) that targets cancer through a unique mechanism of action with two components, selective tumor lysis and activation of the innate and adaptive immune systems. Phase 3 ready.

  • AN0025 (EP4 Antagonist ) solid tumor  

    AN0025 is an investigational, potentially first in class oral EP4 antagonist that is believed to prevent the binding of prostaglandin E2 to its EP4 to change the immunosuppressive character of the tumor microenvironment. Based on preliminary results, it is well tolerated in patients with solid tumors. A Phase 1b combination study with radiotherapy and chemoradiotherapy is ongoing .

  • AN2025 (Buparlisib) HNSCC  

    Buparlisib is an oral pan-PI3K inhibitor that targets all class 1 PI3K isoforms and is active in both hematologic malignancies and solid tumors. It has shown promising efficacy in combination with paclitaxel in head and neck squamous cell carcinoma (HNSCC) and has received a Fast-Track designation from the FDA.

  • Product Indication
  • Ganirelix Acetate Injection Ganirelix is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilisation.
  • Carbetocin Injection Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin — it causes contraction of the uterus.
  • Desmopressin Acetate Tablets Desmopressin is a chemical that is similar to Antidiuretic Hormone (ADH) which is found naturally in the body. It increases urine concentration and decreases urine production. Desmopressin is used to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions, allowing you to sleep through the night without awakening to urinate. It is also used to treat specific types of diabetes insipidus and conditions after head injury or pituitary surgery.

TTechnical reserve: Bivalirudin for Injection, Thymalfasin for Injection, Atosiban Acetate Injection, Terlipressin for Injection, linaclotide Capsule, Degarelix for Injection, Liraglutide Injection, Ziconotide Injection, Insulin Detemir Injection, Teriparatide Injection etc.

We provide technology optimization, preparation technology of peptide and protein drug for a number of well-known domestic pharmaceutical enterprises.

Technical services are mainly related to generic technology of peptide and protein, not involving the new drugs research and development technology secrets.